The International and American Associations for Dental Research (IADR/AADR) have published two reports including a critical review titled “Diet and Dental Caries – the Pivotal Role of Free Sugars Reemphasized.” In this study, authors Aubrey Sheiham, University College London, England; and W. Philip James, London School of Hygiene and Tropical Medicine, England, demonstrate the sensitivity of cariogenesis (the development of caries) to even very low sugars intakes. In this critical review, the authors reviewed the literature on the role of sucrose in the cariogenic process and conclude there is extensive scientific evidence that free sugars are the primary necessary factor in the development of dental caries.