Community water fluoridation (CWF) and other fluoride modalities historically have been and remains the cornerstone for the prevention and control of dental caries. There is extensive evidence on the efficacy and cost‐effectiveness of these interventions as well as assessments of the risks associated with fluoride ingestion. In 2006, the National Research Council identified severe fluorosis as the only documented health effect of fluoride at 2 – 4 mg/L in drinking water. Concentrations recommended for CWF and current dosage schedules for other modalities ensure safety. Systematic reviews on fluorides have identified gaps in knowledge or the need to replicate some of the previous studies under current widespread use of fluorides.