Published in the Journal of Dental Research is a report on a preclinical investigation titled “Flagellin Enhances Saliva IgA Response and Protection of Anti-caries DNA Vaccine,”  Wei Shi the leading Author at the Wuhan Institute of Virology, Chinese Academy of Sciences, and his team of researchers demonstrate that anti-caries DNA vaccines, including pGJA-P/VAX, are promising for preventing dental caries. However, challenges remain because of the low immunogenicity of DNA vaccines.

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